• BTEC Short Courses: Applied Principles and Techniques of Depth Flow Filtration (DFF) and Tangential Flow Filtration (TFF) for BioPharm Downstream Purification

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    Name: BTEC Short Courses: Applied Principles and Techniques of Depth Flow Filtration (DFF) and Tangential Flow Filtration (TFF) for BioPharm Downstream Purification
    Date: October 20, 2020 - October 23, 2020
    Event Description:

    Why should you attend?

    Through participation in this four-day comprehensive filtration course, you will learn the fundamental principles and optimum applied techniques for depth filtration (DFF) and tangential flow filtration (TFF) used today in biopharmaceutical downstream purification.

    The one-day lecture is designed to help individuals gain a solid understanding of the parameters and factors that affect DFF and TFF membrane performance and product recovery for both upstream cell clarification and downstream UF/DF biopharmaceutical applications. Depth filtration (DFF) will cover polymeric membrane and matrix media technologies, and tangential flow filtration (TFF) will cover both flat sheet cassette and hollow fiber element configurations. New advancements will be covered.

    During the three-day hands-on laboratory workshop, DFF and TFF application trials are performed using state-of-the-art benchtop systems. Two full-day sessions are dedicated to cell clarification—with DFF on day one and by TFF on day two. Day three focuses on UF/DF by TFF. Data developed during these trials will be summarized, discussed, and applied to real scale-up system problems and SOP. The principles and techniques presented in the prerequisite lecture course will be applied in this workshop, which is limited to 12 participants.

    Attend and you will learn

    • About filtration technologies and formats currently available for biopharmaceutical downstream purification
    • Current issues related to performance, scale-up, optimization, cleaning (CIP) and methods development through use of case studies
    • How to perform required initial membrane and element characterization
    • How to determine optimum operating conditions that meet trial objectives
    • How to apply the results to make informed, systematic decisions for scale-up and/or process improvements
    • How to perform process runs to include concentration and diafiltration with complete data acquisition and analysis
    • How to perform Clean-in-Place (CIP) to achieve maximum membrane recovery

    Who should attend

    The workshop is designed for engineers, scientists, managers, technical personnel and researchers who require an in-depth review of filtration principles and their application to processes in the areas of process development, manufacturing and quality assurance/validation.

    Attend and you will receive

    • 29.75 hours of instruction (2.9 CEUs) – full 4-day course; 22.5 hours (2.2 CEUs) – 3-day laboratory workshop; 7.25 hours (0.7 CEUs) – 1-day lecture class only
    • Notebook containing all course lecture and lab materials
    • Morning coffee
    • Lunch
    • Afternoon beverage break
    • Certificate of attendance
    Location:
    All courses are offered on site at BTEC, other than online courses. The Golden LEAF BTEC building is located at 850 Oval Drive on NC State University's Centennial Campus.
    Date/Time Information:
    October 20-23
    Fees/Admission:
    • Full four-day course: $3,200
    • Three-day laboratory workshop: $2,400 (One-day lecture is a prerequisite.)
    • One-day lecture class only: $800
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